The Freeman Lab at Dana-Farber/Harvard Medical School is seeking an experienced and motivated research technician to assist with translational immunology research developing new methods of modulating the activity of T-cells for the treatment of human disease.

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The Freeman Lab is known for its fundamental contributions to the field of checkpoint inhibitor therapy, including the discovery of PD-L1 and its interaction with PD-1 and that blockade of the PD-L1/PD-1 pathway enhanced immune responses and could be used for cancer immunotherapy. The successful applicant will join a vibrant research team investigating novel bispecific antibodies that have the potential for use as therapeutics for cancer and autoimmune conditions. Work will involve cell culture, multicolor flow cytometry, and in vivo studies in mice.

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We are seeking a candidate who is enthusiastic, self-motivated, dedicated, possesses excellent organizational and communication skills, is attentive to detail, and works well with others.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

• Examination of animals, routinely monitoring tumor growth and other metrics of therapeutic efficacy.
• Isolate and prepare specimens for examination: blood, mouse tissue, cell lines and primary cells for sorting and flow cytometry analysis.
• Maintain cell lines and primary cells in tissue culture.
• Perform various experimental techniques such as flow cytometry, immunoblotting, immunohistochemistry, RNA-extraction, ELISA, real-time PCR, molecular biology (cloning, mutagenesis), surface plasmon resonance, and protein purification.
• Maintain detailed laboratory records, analyze data, and report experimental results.
• Assist with lab management, including ordering, maintaining laboratory equipment, and preparing reagents and solutions.

SUPERVISORY RESPONSIBILITIES:

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Research Technician

No supervisory responsibilities. Normally receives detailed instructions on all work.

• A BA/BS or equivalent in Biology or related field is required
• Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
• Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
• Ability to analyze information and use logic to address work-related issues and problems.
• Must have attention to detail and be thorough in completing work tasks.
• Ability to work within a team environment.

KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:

• Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
• Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
• Ability to analyze information and use logic to address work-related issues and problems.
• Must have attention to detail and be thorough in completing work tasks.
• Ability to work within a team environment.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

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Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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