Postdoctoral Fellow – Structural Biology and Drug Discovery in RNA Epigenetics
City of Hope
Monrovia, CA
Job posting number: #7296005 (Ref:10028645)
Posted: December 14, 2024
Application Deadline: Open Until Filled
Job Description
Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.
- For consideration, please send a single PDF that includes your CV, a cover letter briefly highlighting your previous research accomplishments and future research goals, and contact information of three scientific mentors (references) to Dr. Jianjun Chen at [email protected] and Dr. Jeff Perry at [email protected]
- Pay Rate: $34.00-$37.54 per hour/$70,720- $78,099 annually
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
We currently have a Postdoctoral Fellowship position in protein crystallography and drug discovery that is available as a joint position in the labs of Dr. Jianjun Chen, Chair of Department of Systems Biology and Director of Center for RNA Biology and Therapeutics, and Dr. Jeff Perry, Assistant Professor in the Department of Molecular Diagnostics and Experimental Therapeutics, at City of Hope Medical Center in Los Angeles, California. The research is focused on fragment - and small molecule-based drug discovery approaches against RNA/DNA epigenetic targets, RNA methylation and post-transcriptional regulation. The research includes determining structures of fragment, RNA probe, and small molecule:protein target co-complexes and using biophysical approaches, including thermal shift assays, isothermal calorimetry and/or surface plasmon resonance.
For more information about Drs. Chen and Perry’s labs, please click on the links below:
As a successful candidate, you will:
- Devise, plan, document and advance science-based projects in structural biology and drug discovery.
- Generate data for grant applications and prepare manuscripts for publication.
- Work in close collaboration with other team members and external collaborators, including presentation of progress internally or externally.
- Train and supervise technical staff.
- Have the unique possibility to drive research towards the development of novel cancer therapies at the interface of science and translation to the clinic and publish high-impact journals.
Your qualifications should include:
- A PhD in biochemistry, biophysics, or related discipline with a strong background in protein crystallography is required.
- Evidence of scientific rigor and excellence as documented by peer-reviewed publications.
- Ability to work in a fast-paced research environment and manage multiple projects and collaborations.
- Strong team player with excellent communication skills and fluency in English, both spoken and written.
City of Hope employees pay is based on the following criteria:work experience, qualifications, and work location.
City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, pleaseclick here.
To learn more about our Comprehensive Benefits, pleaseCLICK HERE.
#PD
The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.
