Summary

We are seeking a highly motivated and well-organized person to lead a team to run a cardio-respiratory phenotyping screen in neonate mice. The screen aims to uncover genes that underlie congenital disease and discover new drugs and other small molecules that can lead to patient treatments. The Research Associate will manage a team including two additional technicians and interface with other lab stake holders. They should have good interpersonal, communication, and organization skills. The pipeline consists of robotic platforms that automatically measures neonate cardio-respiratory function. Data is transferred off the systems for automated analysis on networks storage. Work will focus on 1) managing the team that operates the pipeline and ensuring its smooth operation; 2) organizing experiments and setting screening priorities for genes, drugs, and other models; 3) organizing, analyzing and presenting the resulting data.

Job Duties

• Lead a team to oversee a cardio-respiratory physiological phenotyping pipeline for the discovery of genes associated with congenital pathophysiologies and small molecule candidates for future therapeutic development and treatments.
• Collect tissues for basic histology and tissue clearing in preparation for microscopy.
• Perform mouse colony maintenance including, breeding and weaning, and PCR based genotyping.
• Maintain an organized laboratory and workspace with full documentation inside of our laboratory information management system.
• Supervise two technicians that will assist mouse colony management and run cardio-respiratory physiological assays.

Minimum Qualifications

• Master's degree in Basic Science or a related field.  Experience in lieu of degree will not be accepted.
• Three years of relevant experience typically as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate.

Preferred Qualifications

• Ph.D. degree in neuroscience, physiology, molecular, cell biology, genetics or related field
• Strong interest and experience in either neuroscience, genetics, or physiology
• Good organizational skills, excellent record keeping, attention to detail, and the ability to work well with others
• Experience handling and working with genetically engineered lab mice
• Experience with basic immunohistological laboratory techniques including tissue harvest and processing, thin section microscopy
• Experience with basic molecular laboratory techniques including PCR