Postdoctoral Fellow (Cancer Biology w/ Dr. Raghu Kalluri)
Job posting number: #7076501
Posted: March 29, 2021
Application Deadline: Open Until Filled
Job DescriptionThe Kalluri laboratory at the MD Anderson Cancer Center wants to expand their work on the molecular underpinnings of cancer initiation, progression and metastasis, and to translate the findings into novel therapeutic approaches. The Kalluri laboratory focuses on innovation research in the area of cancer biology with a specific focus on oncogene addiction, tumor microenvironment, stromal biology, exosomes biology, tumor metabolism and tumor immunology. Recent publications on the stromal biology of cancer (Ozdermir et al. 2014, Cancer Cell), exosomes biology in cancer (Kalluri & LeBleu, 2020, Science, Melo et al., 2014 Cancer Cell; Melo et al. 2015, Nature), tumor immunology (Ozdermir et al. 2014, Cancer Cell; Carstens et al. 2017, Nature Communications), metastasis (Zheng et al. 2015, Nature; Lovisa et al. 2015, Nature Medicine), exosomes mediated oncogene targeting (Kamerkar et al. 2017, Nature) and tumor metabolism (LeBleu et al. 2014, Nature Cell Biology, Becker et al. 2020, Cell Reports), have formed the framework for the next set of projects that use innovative technologies such as CRISPR-Cas9, single cell and nuclei sequencing, exosome engineering and mouse modeling to address cutting-edge questions in cancer biology. The Kalluri laboratory strives to transform seminal basic cancer research to inform clinical translation of such findings and will employ any required technology to address important unanswered questions in cancer biology. With strong funding from the NCI, CPRIT Established Investigator Award, and other funding sources, the laboratory is well positioned to exploit the new avenues for fundamental discoveries in cancer and translate such findings into the clinic, exploiting the translational potential of MD Anderson Cancer Center.
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